Featured Publications
Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: A randomized, double-blind, controlled feeding, crossover trial
Nana Gletsu-Miller, Meredith L Wilcox, Lisa A Spence, Amy J Wright, Liana L Guarneiri, Muhammad M Nadeem, Mark J Hutter, Karen L Sprague, Andrew W Brown, Allon N Friedman, Carol F Kirkpatrick, Kevin C Maki
The purpose of this randomized, double-blind, free-living, controlled feeding, crossover study in adults with increased cardiometabolic risk was to assess the effects of replacing energy from solid fats and added sugars with equivalent energy from one avocado daily on cardiometabolic risk factors.
A randomized, double-blind, controlled trial to assess the effects of lactoferrin at two doses vs. active control on immunological and safety parameters in healthy adults
Ross D Peterson, Liana L Guarneiri, Caryn G Adams, Meredith L Wilcox, Anthony J Clark, Nathan P Rudemiller, Kevin C Maki, Carrie-Anne Malinczak
Recombinant human lactoferrin (rhLF) is of commercial interest for immune support as a food ingredient. The objective was to evaluate the immunogenicity/alloimmunization potential of Helaina rhLF (effera™) from K. phaffii over a 28-day period compared to bovine LF (bLF). Study 1 was a randomized, double-blind, parallel arm, controlled trial where 66 healthy adults were randomly allocated to 1 of 3 groups: high-dose rhLF (3.4 g/d), low-dose rhLF (0.34 g/d), or bLF (3.4 g/d). Participants completed a 28-day supplementation period with follow-up visits on Days 28, 56, and 84. Study 2 was a 12-week observational study with no intervention that enrolled 24 healthy adults.
Comparison of the effects of a phospholipid-enhanced fish oil versus krill oil product on plasma levels of eicosapentaenoic and docosahexaenoic acids after acute administration
Liana L Guarneiri, Meredith L Wilcox, Kevin C Maki
This randomized, double-blind, crossover study evaluated the bioavailability of eicosapentaenoic and docosahexaenoic acids (EPA+DHA) in a phospholipid-enhanced fish oil (PEFO) product versus a krill oil (KO) product (337 versus 206 mg EPA+DHA/1 g capsule) in healthy adults (N = 24). The aim of this study was to assess the plasma levels of EPA, DHA, and EPA+DHA following a single capsule of PEFO versus KO products in healthy adult men and women.
Investigation of the Influence of a Bitter Melon Product on Indicators of Cardiometabolic Health in Adults with Prediabetes
Liana L Guarneiri, Meredith L Wilcox, Chen-Meng Kuan, Kevin C Maki
The purpose of this study was to assess the impact of bitter melon extract supplementation on glycemia in individuals with prediabetes.